Cells and Inflammation: Practice Question

A 62 year old male with intermittent hematuria is found to have several stones in his urinary bladder. Biopsy of the bladder mucosa shows squamous epithelium. These findings are described as:
  1. Metaplasia
  2. Hyperplasia
  3. Choristoma
  4. Dysplasia
  5. Hamartoma
Show Answer and Explanations

Metaplasia — Correct answer

Correct. Metaplasia replaces one differentiated cell type with another differentiated cell type; it is reversible.

Hyperplasia

Incorrect. Hyperplasia is an increase in cell production in a normal tissue.

Choristoma

Incorrect. A choristoma is a mass of normal tissue in an abnormal location.

Dysplasia

Incorrect. Dysplasia is abnormal growth and differentiation of tissue.

Hamartoma

Incorrect. A hamartoma is a disorganized mass of tissue normally found at the given location.

Summary

Summary: Metaplasia replaces one differentiated cell type with another differentiated cell type; it is reversible. A hamartoma is a disorganized mass of tissue normally found at a given location. A choristoma is a mass of normal tissue in an abnormal location.
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