Endocrine: Practice Question

Which of the following is not a feature of adrenal adenoma fine needle aspirations?
  1. Mitotic figures
  2. Nuclear molding
  3. Nuclear enlargement
  4. Naked nuclei
  5. Indistinct cell borders
Show Answer and Explanations

Mitotic figures — Correct answer

Correct. Mitotic figures are usually absent in adrenal adenomas.

Nuclear molding

Incorrect. Nuclear molding may be present in adrenal adenomas.

Nuclear enlargement

Incorrect. Focal nuclear enlargement may be present in adrenal adenomas.

Naked nuclei

Incorrect. In adrenal adenomas, naked nuclei stripped of their delicate cytoplasm are frequently present.

Indistinct cell borders

Incorrect. When adrenal adenoma cells are intact, the cell borders are indistinct.

Summary

Summary: Fine needle aspirations of adrenal adenomas typically show round naked nuclei in a frothy background. When intact cells are present, they have abundant cytoplasm and indistinct cell borders. Focal nuclear enlargement and nuclear molding may be present but mitotic figures are absent.
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