Genitourinary: Practice Question

What is the staining pattern of CD117 in seminomas?
  1. Membranous
  2. Nuclear
  3. Cytoplasmic
  4. Perinuclear
Show Answer and Explanations

Membranous — Correct answer

Correct. The staining pattern of CD117 is membranous. CD stands for "cluster of differentiation", which are cell surface molecules.

Nuclear

Incorrect. Nuclear stains would be for proteins such as those involved with transcription and translation, and other nuclear functions.

Cytoplasmic

Incorrect. CD proteins are found on the cell surface.

Perinuclear

Incorrect. CD proteins are found on the cell surface.

Summary

Summary: CD117 shows a membranous staining pattern in seminomas.
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